Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:APRD00546 (Rosuvastatin)
 453 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
C-reactive protein 60
HMG-CoA reductase 57
reductase 45
HDL 32
Sep 30
Mol 16
CRP 16
cytochrome P450 16
insulin 15
ATP 14
apolipoprotein B 14
apolipoprotein 13
endothelial nitric oxide synthase 12
LDL receptor 11
creatine kinase 11
caspase-3 9
OATP1B1 9
polypeptide 8
CYP2C9 8
nitric oxide synthase 8
more...
Disease
atherosclerosis 69
cardiovascular disease 51
dyslipidemia 48
diabetes 46
hypercholesterolemia 45
coronary heart disease 33
myocardial infarction 30
hypertension 28
hyperlipidemia 26
stroke 25
heart failure 20
coronary artery disease 19
metabolic syndrome 18
myopathy 17
ischemia 16
obesity 16
plaque 13
proteinuria 13
type 2 diabetes 9
myocardial ischemia 9
more...
Symptom
myalgia 9
anesthesia 3
weakness 3
asthenia 3
nausea 2
constipation 2
dyspnea 2
angina 2
vomiting 2
abdominal pain 2
fatigue 1
overweight 1
insomnia 1
arthralgia 1
starvation 1
diarrhea 1
functional recovery 1
pain 1
Drug
Rosuvastatin 453
Cardiovasc 30
Rosuvastatin calcium 28
Simvastatin 13
niacin 9
Ezetimibe 7
Pravastatin 6
Lovastatin 5
caffeine 3
Lipitor 3
Lipitor 3
Lipitor 3
Fructose 2
Angiotensin II 1
Poloxamer 1
Darbepoetin alfa 1
Ditropan 1
Efalizumab 1
Elvitegravir 1
nitroglycerin 1
more...
Enzyme
3-hydroxy-3-methylglutaryl coenzyme A reductase 25
creatine kinase 15
mitogen-activated protein kinase 12
alanine aminotransferase 11
caspase-3 9
superoxide dismutase 7
CYP3A4 5
NO synthase 5
3-hydroxy-3-methylglutaryl-CoA reductase 5
ERK 5
catalase 4
NADPH oxidase 4
peroxidase 3
aspartate aminotransferase 3
AST 3
glutathione peroxidase 3
NOS 3
reverse transcriptase 3
protein kinase C 3
alkaline phosphatase 3
more...
Compound
Cardiol 55
Clin 44
Dec 33
Cholesterol 32
glucose 14
ATP 14
Atorvastatin 14
nitric oxide 13
calcium 12
oxygen 12
creatinine 11
Statin 11
water 11
DNA 9
HMG-CoA 8
arginine 7
Pravastatin 6
sodium 5
Ascorbic acid 5
sulfate 4
more...