Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:APRD00546 (
Rosuvastatin
)
453
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Analysis of a secondary end point of the JUPITER trial (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating
Rosuvastatin
) found that a statin reduced the risk of venous thromboembolism (VTE) in apparently healthy people with high levels of C-reactive protein and normal levels of low-density lipoprotein cholesterol (N Engl J Med 2009; 360:1851-1861). Still, pending more study, statins should not be substituted for proven prophylaxis and anticoagulation, especially for patients with recurrent
deep venous thrombosis
, hospitalized patients, postoperative patients, and other patients prone to VTE.
...
PMID:Interpreting the JUPITER trial: statins can prevent VTE, but more study is needed. 2020 Jan 69
