Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:APRD00534 (
Modafinil
)
385
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
20
dopamine transporter
18
orexin
15
GABA
12
ADHD
8
CRL
5
REM
5
cage
5
DAT
4
tyrosine hydroxylase
4
NET
4
cytochrome P450
4
growth hormone
3
serotonin transporter
3
CYP2C9
3
CYP3A4
3
interferon
3
TNF
3
D2R
3
cytokine
3
more...
Disease
narcolepsy
130
sleep disorders
43
depression
39
obstructive sleep apnea
29
cataplexy
26
addiction
18
sleep apnea
18
schizophrenia
17
Parkinson's disease
16
cognitive impairment
15
multiple sclerosis
14
hallucinations
14
ADHD
13
sympathomimetic
8
cancer
7
major depressive disorder
7
sleep disturbances
7
psychosis
7
hypertension
6
Alzheimer's disease
6
more...
Symptom
sleepiness
124
fatigue
52
hypersomnia
25
headache
20
eds
13
insomnia
12
nausea
8
seizures
8
pain
6
agitation
6
decreased appetite
5
dizziness
5
anesthesia
4
tremor
4
spasticity
3
apathy
3
diarrhea
2
dystonia
2
exhaustion
2
vomiting
2
more...
Drug
Modafinil
385
caffeine
8
ENT
4
Monit
3
Armodafinil
3
Atomoxetine
3
Adderall
2
Clonidine
2
Portal
2
Diphenhydramine
1
Triad
1
Zyban
1
Papaverine
1
lysine
1
Pramipexole
1
Remoxipride
1
Tenex
1
MAP
1
Concerta
1
CTX
1
more...
Enzyme
ERK
4
DAT
4
tyrosine hydroxylase
4
CYP3A4
3
mitogen-activated protein kinase
2
acetylcholinesterase
2
superoxide dismutase
2
cholinesterase
2
protein kinase
2
alanine aminotransferase
1
caspase-3
1
pyruvate dehydrogenase
1
CPT
1
CPT
1
monoamine oxidase
1
phosphodiesterase
1
dopamine beta-hydroxylase
1
lipase
1
aspartate aminotransferase
1
pyruvate dehydrogenase
1
more...
Compound
Clin
40
Dec
24
glutamate
18
acetamide
16
acetamide
16
GABA
13
GABA
13
water
10
5-HT
9
sodium
9
caffeine
9
ethanol
8
noradrenaline
8
Methylphenidate
7
Amphetamine
7
Amphetamine
7
Cocaine
7
MPTP
5
NMDA
5
Methamphetamine
4
more...