Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:APRD00530 (Portal)
4,208 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 255
insulin 153
5-hydroxytryptamine 94
Mol 81
glucagon 80
serotonin transporter 64
gut 63
5-HT1A 48
brain-derived neurotrophic factor 46
cytochrome P450 40
somatostatin 36
Net 35
collagen 34
vasopressin 33
cytokine 33
aspartate aminotransferase 30
beta-endorphin 29
albumin 28
superoxide dismutase 25
CYP2D6 25
tumor necrosis factor 24
TNF 24
5-HT2A 24
IL-6 22
lipopolysaccharide 22
alanine aminotransferase 21
ACTH 20
catalase 20
renin 19
caspase-3 19
She 19
CA1 19
5-HT receptor 18
tryptophan hydroxylase 17
endoplasmic reticulum 17
oxytocin 17
hemoglobin 17
casein 17
p53 16
gastrin 16
more...
Disease
depression 442
portal hypertension 396
cirrhosis 307
cancer 219
tumor 215
major depressive disorder 118
hepatocellular carcinoma 116
liver disease 110
varices 104
esophageal varices 79
ischemia 69
diabetes 59
encephalopathy 52
obsessive-compulsive disorder 49
carcinoma 45
chronic liver disease 45
aggression 41
hepatitis 41
metastases 40
stroke 39
chronic hepatitis 37
obesity 37
hypertension 37
liver fibrosis 35
hepatic encephalopathy 35
liver metastases 34
cholestasis 33
sepsis 33
sepsis 31
cholangitis 30
liver cancer 27
SEM 27
Alzheimer's disease 25
anxiety disorders 25
cold 24
hepatitis C 22
alcoholic cirrhosis 22
obstructive jaundice 22
liver cancer 21
biliary obstruction 20
more...
Symptom
pain 51
anesthesia 40
seizures 36
splenomegaly 34
abdominal pain 30
nausea 25
anorexia 22
headache 19
insomnia 19
vomiting 16
sleepiness 15
diarrhea 15
tremor 14
agitation 14
hypothermia 14
despair 11
dizziness 11
fatigue 11
functional recovery 11
hepatomegaly 10
analgesia 8
starvation 8
asthenia 7
overweight 7
acute stress 7
respiratory distress 6
constipation 5
discomfort 5
discomfort 5
weakness 5
lethargy 4
lightheadedness 4
hepatosplenomegaly 4
hypercapnia 4
myoclonus 4
collapse 3
hypersomnia 3
stigma 3
erythema 3
flushing 3
more...
Drug
Portal 4208
Prozac 235
lysine 17
Paxil 14
Paxil 14
Zoloft 14
Paxil 14
Cardiovasc 13
Glucagon 11
Nephron 11
Spectrum 11
caffeine 10
CSF 8
lactose 8
Anafranil 8
Leaf 8
Escitalopram 7
Anafranil 7
Ethanol 7
Monit 7
Fluvoxamine maleate 6
Mirtazapine 6
NH3 6
Tianeptine 6
Agomelatine 6
Dermatol 6
ascorbate 5
DHT 5
DHT 5
Gel 5
Lipiodol 5
MAP 5
nitroglycerin 5
Alanine 4
EE2 4
Horizon 4
Celexa 4
IL-2 4
Reboxetine 4
Dexfenfluramine 4
more...
Enzyme
alanine aminotransferase 38
aspartate aminotransferase 38
mitogen-activated protein kinase 31
superoxide dismutase 28
monoamine oxidase 26
protein kinase 21
catalase 20
renin 19
tryptophan hydroxylase 17
ERK 16
alkaline phosphatase 14
acetylcholinesterase 13
CYP3A4 13
protein kinase C 11
lactate dehydrogenase 10
peroxidase 10
tyrosine hydroxylase 10
caspase-3 9
AST 8
ATPase 8
NO synthase 8
P-glycoprotein 7
glutathione peroxidase 7
GSK 6
pyruvate kinase 6
glutathione S-transferase 6
adenylate cyclase 6
phospholipase C 6
hexokinase 6
thromboplastin 5
luciferase 5
glutaminase 5
phosphofructokinase 5
glutathione reductase 5
reverse transcriptase 5
focal adhesion kinase 5
phosphodiesterase 5
glucose-6-phosphatase 5
PARP 4
collagenase 4
more...
Compound
Clin 339
5-HT 309
Dec 272
glucose 204
water 194
oxygen 101
DNA 86
sodium 77
calcium 68
ethanol 62
noradrenaline 61
ammonia 49
nitric oxide 48
urea 45
DSM 40
tryptophan 40
arginine 39
tryptophan 39
Sertraline 39
tryptophan 36
tryptophan 36
glutamate 35
HCl 34
glutamine 33
acetate 33
potassium 29
alanine 28
Citalopram 28
Paroxetine 26
hydroxyindoleacetic acid 25
nitrogen 24
Fluvoxamine 24
TNF 24
5-hydroxytryptophan 23
Insulin 21
lysine 20
cAMP 19
Imipramine 19
ACTH 19
Imipramine 19
more...