DrugBank:APRD00528 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Target Concepts:

Query: DrugBank:APRD00528 (Monit)
35,110 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)

.

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein
Sep	2177
ICP	235
DDT	233
EPA	193
caspase-3	186
IL-6	182
hemoglobin	180
tumor necrosis factor	167
NO3	165
CO2	163
Bcl-2	158
ash	155
insulin	150
TNF	142
kit	139
C18	132
albumin	127
ANOVA	122
cytokine	119
collagen	115
PI3K	110
AKT	109
CCK	105
PCB	102
superoxide dismutase	100
Pseudomonas	98
p53	95
HCH	94
BOD	93
catalase	91
COD	88
C-reactive protein	87
tap	87
San	83
cytochrome P450	75
mTOR	74
serum albumin	73
CYP2D6	73
PAH	70
TNF-alpha	68
HDL	68
MRI	66
alkaline phosphatase	66
BCR	65
lipopolysaccharide	65
beach	65
p65	63
IL-10	62
ASA	61
TNM	61
interleukin-6	61
GSH	60
vascular endothelial growth factor	60
PCA	58
ERK	57
osteosarcoma	56
IFN	54
UTR	53
p38	53
MAPK	52
lactate dehydrogenase	51
annexin V	51
E-cadherin	51
TLR4	50
cytochrome	49
catenin	49
cage	48
DDD	48
LC3	48
AES	47
CRP	47
gut	46
aspartate aminotransferase	46
glycoprotein	46
SOD	45
CYP3A4	45
matrix metalloproteinase	44
STAT3	43
CYP2C19	42
IL-8	42

Disease
cancer	957
myocardial ischemia	703
tumor	703
hypertension	523
stroke	320
diabetes	303
ICP	235
depression	202
myocardial infarction	188
West	185
heart failure	176
carcinoma	166
breast cancer	160
cold	159
atherosclerosis	158
ash	156
Poland	149
ischemia	146
lung cancer	138
hepatocellular carcinoma	137
cardiovascular disease	127
sepsis	123
obesity	122
type 2 diabetes	119
sepsis	116
gastric cancer	114
epilepsy	114
colorectal cancer	111
Delhi	102
HIV	100
asthma	98
coronary artery disease	92
tumorigenesis	92
Alzheimer's disease	82
chronic obstructive pulmonary disease	78
adenocarcinoma	78
non-small cell lung cancer	77
SEM	77
vaccinia	72
lichen	71
renal disease	69
osteoarthritis	65
acute myocardial infarction	64
tumor growth	63
osteosarcoma	62
tumor progression	62
GSH	61
cirrhosis	61
PCA	58
coronary heart disease	58
renal failure	58
cognitive impairment	55
ovarian cancer	54
rheumatoid arthritis	54
prostate cancer	54
plaque	53
pneumonia	52
osteoporosis	52
metastases	51
Parkinson's disease	49
coma	49
immunodeficiency	49
schizophrenia	49
DDD	48
heart disease	47
abortion	47
cervical cancer	46
congestive heart failure	46
squamous cell carcinoma	46
cerebral ischemia	46
liver disease	45
cardiomyopathy	45
infectious diseases	44
carcinogenesis	44
multiple sclerosis	43
anemia	43
leukemia	43
glioma	43
influenza	43
hyperlipidemia	42

Symptom
anesthesia	636
pain	255
angina	121
seizures	113
acidity	80
analgesia	71
flushing	58
diarrhea	44
agitation	39
nausea	38
overweight	36
respiratory distress	34
headache	34
cough	31
vomiting	31
collapse	29
Wind	28
discomfort	27
tremor	27
fatigue	25
discomfort	25
weakness	22
hypothermia	21
functional recovery	20
low back pain	19
dyspnea	18
chest pain	18
sleepiness	18
nausea and vomiting	17
hypercapnia	16
dizziness	16
hyperoxia	16
Sedation	14
abdominal pain	13
regurgitation	13
thinning	13
exhaustion	12
tachypnea	12
anorexia	11
back pain	11
insomnia	11
cancer pain	10
spasm	10
syncope	10
wheezing	9
hypocapnia	8
exertional angina	8
constipation	8
sore throat	8
arthralgia	8
numbness	8
Hudson	8
cachexia	7
neck pain	7
distraction	7
dystonia	6
leg pain	6
starvation	6
vertigo	6
spasticity	6
sneezing	5
shortness of breath	5
exertional dyspnea	5
ataxia	5
pelvic pain	5
acute stress	5
acute pain	5
rundown	4
dry eye	4
bradypnea	4
Spasmodic Torticollis	4
hemoptysis	4
hoarseness	4
muscle stiffness	4
hypoproteinemia	3
chills	3
emaciation	3
snoring	3
lethargy	3
Postoperative nausea and vomiting	3

Enzyme
luciferase	191
caspase-3	151
superoxide dismutase	138
ERK	138
mitogen-activated protein kinase	128
catalase	111
focal adhesion kinase	78
PAH	70
alkaline phosphatase	68
alanine aminotransferase	65
aspartate aminotransferase	65
lactate dehydrogenase	52
ACE	49
peroxidase	47
acetylcholinesterase	45
CYP3A4	45
glutathione peroxidase	37
urease	37
protein kinase	37
P-glycoprotein	37
urease	36
renin	36
caspase-9	33
reverse transcriptase	33
BIS	33
creatine kinase	32
MAP	31
calcineurin	29
glutathione S-transferase	27
AMP-activated protein kinase	26
PARP	26
MEK	26
cholinesterase	24
ACS	21
AMPK	21
AMPK	21
IMP dehydrogenase	21
thiopurine methyltransferase	20
AST	20
acid phosphatase	19
thrombin	18
caspase-1	18
collagenase	15
GSK	15
caspase-8	15
EPT	14
thromboplastin	14
protein kinase C	13
trypsin	13
CAD	12
CAD	12
CAD	12
ATPase	12
beta-glucuronidase	12
lipase	11
UDP-glucuronosyltransferase	11
MMP	11
gamma-glutamyl transpeptidase	11
glutathione reductase	11
PCP	10
ascorbate peroxidase	10
RNA polymerase	9
CPR	9
invertase	9
APC	9
tissue plasminogen activator	9
SST	8
dihydropyrimidine dehydrogenase	8
cdc2	8
MMP-3	8
PKG	8
proteasome	8
beta-lactamase	8
xanthine oxidase	8
aldehyde dehydrogenase	7
dihydropyrimidine dehydrogenase	7
sulfatase	7
laccase	7
aldehyde dehydrogenase	7
prostate-specific antigen	7