Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:APRD00396 (
Estrogens
)
2,250
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
estrogen receptor
525
Mol
230
aromatase
193
Sep
139
estrogen receptor alpha
85
insulin
84
ER beta
82
Aromatase
57
prolactin
56
ESR1
41
cytokine
39
androgen receptor
36
Gen
36
progesterone receptor
35
GPR30
34
nuclear receptor
33
collagen
28
ESR2
28
cytochrome P450
25
FSH
25
more...
Disease
breast cancer
353
cancer
258
tumor
171
osteoporosis
104
uterus
95
carcinogenesis
79
MCF
77
endometrial cancer
63
Alzheimer's disease
54
prostate cancer
50
Steroids
50
atherosclerosis
49
cardiovascular disease
49
carcinoma
48
obesity
46
diabetes
43
hypertension
43
stroke
39
tumorigenesis
35
systemic lupus erythematosus
32
more...
Symptom
pain
24
menopausal symptoms
18
masculinization
15
seizures
15
hot flushes
12
nausea
10
hot flashes
9
headache
8
vomiting
6
anesthesia
6
memory loss
5
POA
4
collapse
3
chorea
3
abdominal pain
3
fatigue
3
overweight
3
diarrhea
3
discomfort
2
angina
2
more...
Drug
Estrogens
2250
EE2
112
ICI
74
MAP
52
Premarin
9
Raloxifene
9
Dermatol
7
PTH
6
Estriol
6
ENT
5
DHT
5
DHT
5
Norplant
5
Cardiovasc
5
IFN-gamma
4
DMAP
4
Luteinizing
4
lysine
3
Growth hormone
3
Growth hormone
3
more...
Enzyme
mitogen-activated protein kinase
59
protein kinase
33
ERK
28
luciferase
25
alkaline phosphatase
15
protein kinase C
14
cdc2
13
sulfatase
11
renin
9
phosphatidylinositol 3-kinase
9
NO synthase
9
focal adhesion kinase
9
HSD
9
caspase-3
8
peroxidase
7
catalase
7
reverse transcriptase
7
proteasome
5
collagenase
5
estrogen sulfotransferase
5
more...
Compound
Estrogen
219
Estrogen
193
DNA
169
Dec
163
Estradiol
108
Clin
104
calcium
90
ICI
74
water
68
acetate
51
glucose
48
Progesterone
47
nitric oxide
42
oxygen
42
sulfate
34
Tamoxifen
29
Premarin
29
Tamoxifen
29
Testosterone
27
Testosterone
27
more...