Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:APRD00396 (Estrogens)
2,250 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
estrogen receptor 525
Mol 230
aromatase 193
Sep 139
estrogen receptor alpha 85
insulin 84
ER beta 82
Aromatase 57
prolactin 56
ESR1 41
cytokine 39
androgen receptor 36
Gen 36
progesterone receptor 35
GPR30 34
nuclear receptor 33
collagen 28
ESR2 28
cytochrome P450 25
FSH 25
more...
Disease
breast cancer 353
cancer 258
tumor 171
osteoporosis 104
uterus 95
carcinogenesis 79
MCF 77
endometrial cancer 63
Alzheimer's disease 54
prostate cancer 50
Steroids 50
atherosclerosis 49
cardiovascular disease 49
carcinoma 48
obesity 46
diabetes 43
hypertension 43
stroke 39
tumorigenesis 35
systemic lupus erythematosus 32
more...
Symptom
pain 24
menopausal symptoms 18
masculinization 15
seizures 15
hot flushes 12
nausea 10
hot flashes 9
headache 8
vomiting 6
anesthesia 6
memory loss 5
POA 4
collapse 3
chorea 3
abdominal pain 3
fatigue 3
overweight 3
diarrhea 3
discomfort 2
angina 2
more...
Drug
Estrogens 2250
EE2 112
ICI 74
MAP 52
Premarin 9
Raloxifene 9
Dermatol 7
PTH 6
Estriol 6
ENT 5
DHT 5
DHT 5
Norplant 5
Cardiovasc 5
IFN-gamma 4
DMAP 4
Luteinizing 4
lysine 3
Growth hormone 3
Growth hormone 3
more...
Enzyme
mitogen-activated protein kinase 59
protein kinase 33
ERK 28
luciferase 25
alkaline phosphatase 15
protein kinase C 14
cdc2 13
sulfatase 11
renin 9
phosphatidylinositol 3-kinase 9
NO synthase 9
focal adhesion kinase 9
HSD 9
caspase-3 8
peroxidase 7
catalase 7
reverse transcriptase 7
proteasome 5
collagenase 5
estrogen sulfotransferase 5
more...
Compound
Estrogen 219
Estrogen 193
DNA 169
Dec 163
Estradiol 108
Clin 104
calcium 90
ICI 74
water 68
acetate 51
glucose 48
Progesterone 47
nitric oxide 42
oxygen 42
sulfate 34
Tamoxifen 29
Premarin 29
Tamoxifen 29
Testosterone 27
Testosterone 27
more...