Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:APRD00379 (
Sumatran
)
310
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Several 3-alkylphenols including 3-undecylphenol, which was isolated from a
Sumatran
rainforest plant, were synthesized to investigate their antinematodal activity against the phytopathogenic nematodes, Bursapherencus xylophilus. A three-step synthesis involving the treatment of
2-cyclohexen-1-one
with the Grignard reagent, oxidation of the resulting 1-alkyl-2-cyclohexen-1-ol and subsequent aromatization of 3-alkyl-
2-cyclohexen-1-one
successfully afforded such phenols. Among the 3-alkylphenols, 3-nonylphenol showed the highest activity, while 3-decylphenol and 3-undecylphenol also showed high activity.
...
PMID:Synthesis and antinematodal activity of 3-n-alkylphenols. 1556 83
