Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:APRD00369 (ROS)
19,271 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ROS 19271
caspase-3 1415
GSH 1394
Mol 1241
Sep 1130
ATP 1103
catalase 1061
SOD 990
Bcl-2 956
TNF 906
superoxide dismutase 899
RNS 827
p53 825
MAPK 679
p38 663
Nrf2 640
IL-6 639
JNK 616
cytochrome c 542
cytokine 537
ERK 495
PI3K 465
CAT 456
insulin 429
caspase-9 409
inducible nitric oxide synthase 407
NAC 378
osteosarcoma 373
glutathione peroxidase 367
LPS 364
NADPH 364
AKT 359
PARP 351
HO-1 342
endoplasmic reticulum 341
ERK1 329
mTOR 327
LDH 325
lipopolysaccharide 317
antioxidant enzyme 312
more...
Disease
cancer 2944
tumor 1570
GSH 1394
diabetes 574
breast cancer 470
Alzheimer's disease 422
ischemia 416
osteosarcoma 393
tumor growth 390
MCF 378
lung cancer 313
hepatocellular carcinoma 294
atherosclerosis 290
Parkinson's disease 285
carcinoma 248
obesity 223
melanoma 217
carcinogenesis 211
hypertension 203
leukemia 199
neuroblastoma 189
hyperglycemia 185
tumorigenesis 181
cold 173
adenocarcinoma 171
colon cancer 166
stroke 157
prostate cancer 152
tumor progression 150
type 2 diabetes 149
cardiovascular disease 148
heart failure 145
TEM 141
TEM 139
colorectal cancer 132
non-small cell lung cancer 130
ATM 116
glioma 112
diabetic nephropathy 108
liver cancer 104
more...
Symptom
collapse 115
starvation 91
pain 57
hyperoxia 29
fatigue 27
skin damage 25
anesthesia 25
weakness 24
respiratory distress 23
seizures 23
functional recovery 19
exhaustion 17
diarrhea 15
ataxia 15
acidity 14
cachexia 14
HSA 14
memory loss 13
hypothermia 12
cough 10
overweight 10
splenomegaly 9
acute stress 8
thinning 7
erythema 7
vomiting 7
myalgia 6
headache 5
abdominal pain 5
tremor 5
cerebellar ataxia 4
analgesia 4
nausea 4
pelvic pain 4
angina 4
agitation 3
stigma 3
discomfort 3
dry eye 3
anorexia 3
more...
Drug
ROS 19271
ascorbate 295
NADH 164
vitamin E 110
ZnO 97
PTH 95
Indomethacin 89
Glutathione 76
MAP 72
lysine 66
Dermatol 48
Parkin 45
Parkin 45
Photofrin 43
TiO2 43
Heme 41
Cardiovasc 39
IL-2 38
Monit 34
Gel 32
CSF 31
NBT 27
Nitric Oxide 27
Angiotensin II 27
Vitamin E 27
FAD 25
citric acid 25
IFN-gamma 25
Leaf 25
Ethanol 24
caffeine 24
ALA 24
Arsenic trioxide 24
Mutagen 21
TAC 20
ABC 20
BH4 20
MRC 17
Capsicum 16
CAM 16
more...
Enzyme
superoxide dismutase 1815
mitogen-activated protein kinase 1484
catalase 1463
caspase-3 1073
ERK 738
NADPH oxidase 696
NADPH oxidase 654
PARP 412
peroxidase 384
glutathione peroxidase 371
caspase-9 319
AMP-activated protein kinase 308
protein kinase 278
AMPK 259
complex I 251
AMPK 247
protein kinase C 247
glutathione reductase 227
glutathione S-transferase 215
ATPase 181
lactate dehydrogenase 171
alkaline phosphatase 165
focal adhesion kinase 157
alanine aminotransferase 154
luciferase 154
MMP 149
caspase-8 149
NQO1 148
aspartate aminotransferase 143
caspase-1 142
proteasome 134
MEK 133
ascorbate peroxidase 131
xanthine oxidase 105
NOS 102
AST 100
DCF 89
ACS 87
thioredoxin reductase 76
succinate dehydrogenase 75
more...
Compound
oxygen 3903
DNA 2746
GSH 1438
GSH 1438
Dec 1303
ATP 1103
glucose 998
hydrogen 933
calcium 915
TNF 906
nitrogen 900
water 885
MDA 832
N-acetylcysteine 679
H2O2 660
cysteine 657
MTT 653
nitric oxide 606
CAT 458
CAT 456
CAT 456
iron 418
Panam 379
NADPH 365
NADPH 364
sodium 347
Clin 322
copper 316
salt 306
phosphate 290
zinc 233
NAD 219
tyrosine 218
ethanol 218
GSSG 212
cadmium 206
proline 196
glutamate 190
NAD 186
DPPH 185
more...