Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:APRD00369 (
ROS
)
19,271
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ROS
19271
caspase-3
1415
GSH
1394
Mol
1241
Sep
1130
ATP
1103
catalase
1061
SOD
990
Bcl-2
956
TNF
906
superoxide dismutase
899
RNS
827
p53
825
MAPK
679
p38
663
Nrf2
640
IL-6
639
JNK
616
cytochrome c
542
cytokine
537
ERK
495
PI3K
465
CAT
456
insulin
429
caspase-9
409
inducible nitric oxide synthase
407
NAC
378
osteosarcoma
373
glutathione peroxidase
367
LPS
364
NADPH
364
AKT
359
PARP
351
HO-1
342
endoplasmic reticulum
341
ERK1
329
mTOR
327
LDH
325
lipopolysaccharide
317
antioxidant enzyme
312
more...
Disease
cancer
2944
tumor
1570
GSH
1394
diabetes
574
breast cancer
470
Alzheimer's disease
422
ischemia
416
osteosarcoma
393
tumor growth
390
MCF
378
lung cancer
313
hepatocellular carcinoma
294
atherosclerosis
290
Parkinson's disease
285
carcinoma
248
obesity
223
melanoma
217
carcinogenesis
211
hypertension
203
leukemia
199
neuroblastoma
189
hyperglycemia
185
tumorigenesis
181
cold
173
adenocarcinoma
171
colon cancer
166
stroke
157
prostate cancer
152
tumor progression
150
type 2 diabetes
149
cardiovascular disease
148
heart failure
145
TEM
141
TEM
139
colorectal cancer
132
non-small cell lung cancer
130
ATM
116
glioma
112
diabetic nephropathy
108
liver cancer
104
more...
Symptom
collapse
115
starvation
91
pain
57
hyperoxia
29
fatigue
27
skin damage
25
anesthesia
25
weakness
24
respiratory distress
23
seizures
23
functional recovery
19
exhaustion
17
diarrhea
15
ataxia
15
acidity
14
cachexia
14
HSA
14
memory loss
13
hypothermia
12
cough
10
overweight
10
splenomegaly
9
acute stress
8
thinning
7
erythema
7
vomiting
7
myalgia
6
headache
5
abdominal pain
5
tremor
5
cerebellar ataxia
4
analgesia
4
nausea
4
pelvic pain
4
angina
4
agitation
3
stigma
3
discomfort
3
dry eye
3
anorexia
3
more...
Drug
ROS
19271
ascorbate
295
NADH
164
vitamin E
110
ZnO
97
PTH
95
Indomethacin
89
Glutathione
76
MAP
72
lysine
66
Dermatol
48
Parkin
45
Parkin
45
Photofrin
43
TiO2
43
Heme
41
Cardiovasc
39
IL-2
38
Monit
34
Gel
32
CSF
31
NBT
27
Nitric Oxide
27
Angiotensin II
27
Vitamin E
27
FAD
25
citric acid
25
IFN-gamma
25
Leaf
25
Ethanol
24
caffeine
24
ALA
24
Arsenic trioxide
24
Mutagen
21
TAC
20
ABC
20
BH4
20
MRC
17
Capsicum
16
CAM
16
more...
Enzyme
superoxide dismutase
1815
mitogen-activated protein kinase
1484
catalase
1463
caspase-3
1073
ERK
738
NADPH oxidase
696
NADPH oxidase
654
PARP
412
peroxidase
384
glutathione peroxidase
371
caspase-9
319
AMP-activated protein kinase
308
protein kinase
278
AMPK
259
complex I
251
AMPK
247
protein kinase C
247
glutathione reductase
227
glutathione S-transferase
215
ATPase
181
lactate dehydrogenase
171
alkaline phosphatase
165
focal adhesion kinase
157
alanine aminotransferase
154
luciferase
154
MMP
149
caspase-8
149
NQO1
148
aspartate aminotransferase
143
caspase-1
142
proteasome
134
MEK
133
ascorbate peroxidase
131
xanthine oxidase
105
NOS
102
AST
100
DCF
89
ACS
87
thioredoxin reductase
76
succinate dehydrogenase
75
more...
Compound
oxygen
3903
DNA
2746
GSH
1438
GSH
1438
Dec
1303
ATP
1103
glucose
998
hydrogen
933
calcium
915
TNF
906
nitrogen
900
water
885
MDA
832
N-acetylcysteine
679
H2O2
660
cysteine
657
MTT
653
nitric oxide
606
CAT
458
CAT
456
CAT
456
iron
418
Panam
379
NADPH
365
NADPH
364
sodium
347
Clin
322
copper
316
salt
306
phosphate
290
zinc
233
NAD
219
tyrosine
218
ethanol
218
GSSG
212
cadmium
206
proline
196
glutamate
190
NAD
186
DPPH
185
more...