Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:APRD00345 (ICI)
 5,388 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
estrogen receptor 1314
beta 1 566
Mol 492
Sep 361
opioid receptor 215
progesterone receptor 150
estrogen receptor alpha 146
AMP 120
ER beta 119
oestrogen receptor 117
adenylate cyclase 117
BRL 108
aromatase 102
insulin 97
ERK1 91
nitric oxide synthase 91
pS2 88
MAPK 79
Leu5 77
cytokine 76
more...
Disease
breast cancer 608
MCF 466
cancer 382
tumor 213
uterus 161
asthma 96
carcinoma 86
pertussis 73
hypertension 70
prostate cancer 66
depression 61
osteoporosis 60
carcinogenesis 55
heart failure 51
Steroids 48
tumor growth 48
malaria 47
sympathomimetic 45
NAME 45
ischemia 43
more...
Symptom
pain 70
analgesia 35
anesthesia 30
tremor 22
seizures 18
hypothermia 17
angina 8
hot flushes 8
menopausal symptoms 8
dyspnea 7
acute stress 7
diarrhea 7
bone pain 7
cough 6
exhaustion 6
hot flashes 5
fatigue 4
discomfort 4
discomfort 4
anorexia 3
more...
Drug
ICI 5388
EE2 165
Cardiovasc 81
Estrogens 74
Fulvestrant 74
Atenolol 54
Zoladex 46
Zoladex 46
MAP 44
Nephron 43
Raloxifene 32
Salbutamol 31
Dermatol 17
ROS 16
Forskolin 16
caffeine 16
Casodex 13
Clonidine 12
Fenoterol 12
Peridex 11
more...
Enzyme
mitogen-activated protein kinase 251
protein kinase 168
luciferase 145
ERK 122
adenylate cyclase 118
protein kinase C 80
phosphodiesterase 68
NO synthase 58
MEK 57
alkaline phosphatase 55
caspase-3 41
phosphatidylinositol 3-kinase 36
aldose reductase 35
catalase 35
phospholipase C 34
peroxidase 33
renin 31
cathepsin D 28
MPP 27
ATPase 26
more...
Compound
ICI 5338
Dec 413
noradrenaline 265
DNA 263
Estradiol 255
calcium 243
cAMP 241
Estrogen 221
Estrogen 215
Clin 192
tyrosine 154
Isoproterenol 148
Tamoxifen 139
Tamoxifen 134
nitric oxide 132
sodium 128
MDA 128
AMP 125
Phe 122
glucose 115
more...