Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: DrugBank:APRD00249 (Mutagen)
5,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Mol 2811
HN2 333
Sep 138
p53 135
microsomal 85
hypoxanthine-guanine phosphoribosyltransferase 81
HPRT 62
H2AX 57
GSH 52
cytochrome P450 47
histone 43
xenobiotic 42
thymus 40
catalase 40
CD59 36
GSTM1 35
endonuclease 33
X-linked 33
superoxide dismutase 32
CYP1A1 32
glutathione S-transferase 32
ATP 31
telomeric 31
NADPH 31
spermatozoa 31
GSTT1 30
cytochrome P-450 30
caspase-3 30
thymidine kinase 27
ACS 26
HN1 25
RET 25
NMR 25
P450 25
XRCC1 24
Bcl-2 23
GST 22
CYP2E1 22
DBA 22
peroxidase 22
more...
Disease
cancer 707
tumor 351
carcinogenesis 253
breast cancer 119
lymphoma 109
lung cancer 65
leukemia 56
GSH 52
MCF 47
tumorigenesis 44
carcinoma 43
depression 32
ATM 32
adenocarcinoma 28
hepatocellular carcinoma 27
plaque 26
diabetes 25
tumor growth 24
bladder cancer 24
Hodgkin's disease 24
HIV 24
DBA 22
colorectal cancer 21
anemia 21
colon cancer 21
cleft palate 20
tumor progression 19
melanoma 19
xeroderma pigmentosum 19
cold 17
squamous cell carcinoma 17
pancreatic cancer 16
skin cancer 16
CREST 15
SEM 15
Fanconi 15
XPD 14
prostate cancer 14
obesity 14
sarcoma 13
more...
Symptom
anesthesia 8
pain 6
starvation 5
collapse 4
fatigue 3
hypothermia 3
nausea 3
ataxia 3
acidity 3
skin damage 3
thinning 3
acute stress 2
vomiting 2
exertional dyspnea 2
Hudson 2
torticollis 2
Wind 2
dyspnea 2
constipation 1
eds 1
hyperoxia 1
diarrhea 1
Neuropathic pain 1
clubbing 1
DNA marker 1
discomfort 1
masculinization 1
cerebellar ataxia 1
agitation 1
bone pain 1
cough 1
weakness 1
general problem 1
erythema 1
wheezing 1
chills 1
discomfort 1
chest pain 1
HSA 1
respiratory distress 1
more...
Drug
Mutagen 5946
caffeine 41
ascorbate 26
ROS 21
CTX 21
AZT 19
AZT 19
TiO2 16
Adriamycin 16
ZnO 11
EPA 10
Mustargen 9
PCB 7
Gel 7
Leaf 7
Etoposide 7
Dermatol 7
Glutathione 7
vitamin E 7
lysine 6
VCR 6
Arsenic trioxide 6
MAP 6
CSF 6
BH4 5
NADH 5
lactose 5
TAC 5
DNase I 5
Ethanol 4
Award 4
Indomethacin 4
G418 4
CTA 4
Monit 4
MRC 4
ABC 4
FeCl3 4
citric acid 4
BLM 4
more...
Enzyme
hypoxanthine-guanine phosphoribosyltransferase 57
ERK 56
topoisomerase 45
glutathione S-transferase 45
catalase 42
topoisomerase 39
superoxide dismutase 37
endonuclease 33
DNA polymerase 31
peroxidase 30
thymidine kinase 27
mitogen-activated protein kinase 27
ACS 26
caspase-3 25
protein kinase 19
reverse transcriptase 18
alkaline phosphatase 18
PARP 16
luciferase 15
PAH 15
collagenase 15
trypsin 15
beta-galactosidase 14
glutathione peroxidase 14
microsomal epoxide hydrolase 13
PCE 13
N-acetyltransferase 12
ATPase 12
xanthine oxidase 12
ornithine decarboxylase 12
beta-glucuronidase 11
lactate dehydrogenase 11
alanine aminotransferase 10
focal adhesion kinase 9
gamma-glutamyl transpeptidase 9
demethylase 9
soluble epoxide hydrolase 8
Fpg protein 8
proteasome 8
caspase-8 8
more...
Compound
DNA 2033
HN2 336
water 328
nitrogen 247
Dec 242
pyrene 214
oxygen 208
sodium 141
methyl methanesulfonate 111
hydrogen 108
anthracene 88
EMS 87
benzene 72
DBA 63
GSH 61
GSH 61
ethanol 58
acetate 57
iron 55
acrylamide 55
4-mercaptobenzoic acid 54
His 53
cadmium 49
phosphate 49
DMSO 49
aflatoxin B1 49
MDA 46
silver 44
potassium 43
sulfate 42
pyrimidine 41
caffeine 41
pyrimidine 41
ENU 39
copper 38
glucose 36
calcium 36
cysteine 35
salt 35
pyridine 35
more...