Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:APRD00249 (
Mutagen
)
5,946
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
2811
HN2
333
Sep
138
p53
135
microsomal
85
hypoxanthine-guanine phosphoribosyltransferase
81
HPRT
62
H2AX
57
GSH
52
cytochrome P450
47
histone
43
xenobiotic
42
thymus
40
catalase
40
CD59
36
GSTM1
35
endonuclease
33
X-linked
33
superoxide dismutase
32
CYP1A1
32
glutathione S-transferase
32
ATP
31
telomeric
31
NADPH
31
spermatozoa
31
GSTT1
30
cytochrome P-450
30
caspase-3
30
thymidine kinase
27
ACS
26
HN1
25
RET
25
NMR
25
P450
25
XRCC1
24
Bcl-2
23
GST
22
CYP2E1
22
DBA
22
peroxidase
22
more...
Disease
cancer
707
tumor
351
carcinogenesis
253
breast cancer
119
lymphoma
109
lung cancer
65
leukemia
56
GSH
52
MCF
47
tumorigenesis
44
carcinoma
43
depression
32
ATM
32
adenocarcinoma
28
hepatocellular carcinoma
27
plaque
26
diabetes
25
tumor growth
24
bladder cancer
24
Hodgkin's disease
24
HIV
24
DBA
22
colorectal cancer
21
anemia
21
colon cancer
21
cleft palate
20
tumor progression
19
melanoma
19
xeroderma pigmentosum
19
cold
17
squamous cell carcinoma
17
pancreatic cancer
16
skin cancer
16
CREST
15
SEM
15
Fanconi
15
XPD
14
prostate cancer
14
obesity
14
sarcoma
13
more...
Symptom
anesthesia
8
pain
6
starvation
5
collapse
4
fatigue
3
hypothermia
3
nausea
3
ataxia
3
acidity
3
skin damage
3
thinning
3
acute stress
2
vomiting
2
exertional dyspnea
2
Hudson
2
torticollis
2
Wind
2
dyspnea
2
constipation
1
eds
1
hyperoxia
1
diarrhea
1
Neuropathic pain
1
clubbing
1
DNA marker
1
discomfort
1
masculinization
1
cerebellar ataxia
1
agitation
1
bone pain
1
cough
1
weakness
1
general problem
1
erythema
1
wheezing
1
chills
1
discomfort
1
chest pain
1
HSA
1
respiratory distress
1
more...
Drug
Mutagen
5946
caffeine
41
ascorbate
26
ROS
21
CTX
21
AZT
19
AZT
19
TiO2
16
Adriamycin
16
ZnO
11
EPA
10
Mustargen
9
PCB
7
Gel
7
Leaf
7
Etoposide
7
Dermatol
7
Glutathione
7
vitamin E
7
lysine
6
VCR
6
Arsenic trioxide
6
MAP
6
CSF
6
BH4
5
NADH
5
lactose
5
TAC
5
DNase I
5
Ethanol
4
Award
4
Indomethacin
4
G418
4
CTA
4
Monit
4
MRC
4
ABC
4
FeCl3
4
citric acid
4
BLM
4
more...
Enzyme
hypoxanthine-guanine phosphoribosyltransferase
57
ERK
56
topoisomerase
45
glutathione S-transferase
45
catalase
42
topoisomerase
39
superoxide dismutase
37
endonuclease
33
DNA polymerase
31
peroxidase
30
thymidine kinase
27
mitogen-activated protein kinase
27
ACS
26
caspase-3
25
protein kinase
19
reverse transcriptase
18
alkaline phosphatase
18
PARP
16
luciferase
15
PAH
15
collagenase
15
trypsin
15
beta-galactosidase
14
glutathione peroxidase
14
microsomal epoxide hydrolase
13
PCE
13
N-acetyltransferase
12
ATPase
12
xanthine oxidase
12
ornithine decarboxylase
12
beta-glucuronidase
11
lactate dehydrogenase
11
alanine aminotransferase
10
focal adhesion kinase
9
gamma-glutamyl transpeptidase
9
demethylase
9
soluble epoxide hydrolase
8
Fpg protein
8
proteasome
8
caspase-8
8
more...
Compound
DNA
2033
HN2
336
water
328
nitrogen
247
Dec
242
pyrene
214
oxygen
208
sodium
141
methyl methanesulfonate
111
hydrogen
108
anthracene
88
EMS
87
benzene
72
DBA
63
GSH
61
GSH
61
ethanol
58
acetate
57
iron
55
acrylamide
55
4-mercaptobenzoic acid
54
His
53
cadmium
49
phosphate
49
DMSO
49
aflatoxin B1
49
MDA
46
silver
44
potassium
43
sulfate
42
pyrimidine
41
caffeine
41
pyrimidine
41
ENU
39
copper
38
glucose
36
calcium
36
cysteine
35
salt
35
pyridine
35
more...