Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: DrugBank:APRD00249 (
Mutagen
)
5,946
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
2811
HN2
333
Sep
138
p53
135
microsomal
85
hypoxanthine-guanine phosphoribosyltransferase
81
HPRT
62
H2AX
57
GSH
52
cytochrome P450
47
histone
43
xenobiotic
42
catalase
40
thymus
40
CD59
36
GSTM1
35
X-linked
33
endonuclease
33
superoxide dismutase
32
glutathione S-transferase
32
more...
Disease
cancer
707
tumor
351
carcinogenesis
253
breast cancer
119
lymphoma
109
lung cancer
65
leukemia
56
GSH
52
MCF
47
tumorigenesis
44
carcinoma
43
depression
32
ATM
32
adenocarcinoma
28
hepatocellular carcinoma
27
plaque
26
diabetes
25
HIV
24
tumor growth
24
bladder cancer
24
more...
Symptom
anesthesia
8
pain
6
starvation
5
collapse
4
fatigue
3
acidity
3
ataxia
3
skin damage
3
hypothermia
3
nausea
3
thinning
3
dyspnea
2
Wind
2
acute stress
2
Hudson
2
exertional dyspnea
2
torticollis
2
vomiting
2
bone pain
1
weakness
1
more...
Drug
Mutagen
5946
caffeine
41
ascorbate
26
CTX
21
ROS
21
AZT
19
AZT
19
TiO2
16
Adriamycin
16
ZnO
11
EPA
10
Mustargen
9
PCB
7
Glutathione
7
Gel
7
Dermatol
7
Etoposide
7
Leaf
7
vitamin E
7
CSF
6
more...
Enzyme
hypoxanthine-guanine phosphoribosyltransferase
57
ERK
56
glutathione S-transferase
45
topoisomerase
45
catalase
42
topoisomerase
39
superoxide dismutase
37
endonuclease
33
DNA polymerase
31
peroxidase
30
thymidine kinase
27
mitogen-activated protein kinase
27
ACS
26
caspase-3
25
protein kinase
19
alkaline phosphatase
18
reverse transcriptase
18
PARP
16
luciferase
15
trypsin
15
more...
Compound
DNA
2033
HN2
336
water
328
nitrogen
247
Dec
242
pyrene
214
oxygen
208
sodium
141
methyl methanesulfonate
111
hydrogen
108
anthracene
88
EMS
87
benzene
72
DBA
63
GSH
61
GSH
61
ethanol
58
acetate
57
iron
55
acrylamide
55
more...