Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: DrugBank:APRD00171 (Arsenic trioxide)
1,276 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein caspase-3 95 Sep 83 Mol 80 GSH 71 Bcl-2 67 PML 56 p53 56 all-trans 48 p38 48 JNK 37 cytochrome c 36 catalase 34 ERK 28 MAPK 28 MMA 27 superoxide dismutase 26 ROS 24 p21 24 caspase-9 24 PI3K 23 more...

Disease acute promyelocytic leukemia 362 cancer 263 leukemia 148 tumor 133 GSH 71 acute myeloid leukemia 57 PML 56 multiple myeloma 49 hepatocellular carcinoma 42 carcinogenesis 41 lymphoma 36 solid tumor 31 breast cancer 29 MMA 27 lung cancer 26 chronic myeloid leukemia 25 tumor growth 25 MCF 23 carcinoma 22 hematologic malignancies 20 more...

Symptom collapse 5 vomiting 4 pain 4 diarrhea 4 nausea 3 fatigue 3 abdominal pain 2 starvation 2 dyspnea 2 shortness of breath 1 numbness 1 anesthesia 1 hyperoxia 1 constipation 1 acute pain 1 hemiplegia 1 Ill 1 hepatomegaly 1 abdominal cramps 1 headache 1 more...

Drug Arsenic trioxide 1276 ROS 24 ascorbate 7 NADH 6 ADM 6 Mutagen 6 Cardiovasc 6 Bortezomib 5 G-CSF 4 Sorafenib 4 Imatinib 4 Monit 3 anti-CD33 3 AZT 3 Bevacizumab 3 Lenalidomide 3 Gleevec 3 Retinoic Acid 3 Mepolizumab 3 AZT 3 more...

Enzyme mitogen-activated protein kinase 99 caspase-3 73 catalase 41 superoxide dismutase 36 ERK 32 protein kinase 27 PARP 26 MEK 26 arsenite oxidase 20 caspase-9 19 glutathione peroxidase 19 proteasome 17 luciferase 16 ATPase 14 focal adhesion kinase 13 lactate dehydrogenase 11 protein kinase C 11 glutathione S-transferase 11 caspase-8 10 cdc2 8 more...

Compound Arsenite 588 DNA 161 oxygen 149 water 135 Arsenic 130 sodium 108 Dec 105 GSH 74 GSH 74 retinoic acid 70 dimethylarsinic acid 46 dimethylarsinic acid 45 cysteine 43 dimethylarsinic acid 42 dimethylarsinic acid 42 phosphate 42 dimethylarsinic acid 42 dimethylarsinic acid 42 calcium 41 iron 40 more...

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